Basic Revia Information

• INN (International Nonproprietary Name): Naltrexone hydrochloride

• Brand names available in United Kingdom: Revia, Vivitrol

• ATC Code: N07BB04

• Forms & dosages (e.g., tablets, injections, creams):

• 50 mg tablets
• 380 mg injectable, for monthly use

• Manufacturers in United Kingdom: Various generic manufacturers, including Teva and Accord Healthcare
• Registration status in United Kingdom: Prescription-only medication

• OTC / Rx classification: Rx only

Everyday Use & Best Practices

Consistency is key when using Revia, as it's crucial for maintaining stable levels in the body. For most patients, morning dosing is highly recommended. Aligning your medication schedule with your daily routine not only helps in remembering your dose but also reduces the risk of forgetting to take it later in the day.

Taking With or Without Meals

One of the advantages of Revia is that it can be taken with or without food, which suits various lifestyles. In the UK, typical meal timings can impact medication adherence. Here are some tips:

• If taking in the morning, consider having it with breakfast to make it a part of your routine.
• For evening doses, ensure it's taken before your last meal to help minimise any potential stomach discomfort.
• Stick to regular meal patterns; this can help keep your metabolism steady especially while on Revia.

Safety Priorities

While Revia can be an effective treatment option for opioid and alcohol use disorders, certain individuals should avoid it altogether. According to MHRA warnings, those with a history of opioid dependency should not use Revia. It can precipitate withdrawal symptoms if opioids are still present in the body. Additionally, anyone suffering from acute hepatitis or severe liver damage should avoid this medication due to the potential for exacerbating liver issues.

Activities to Limit

Patients using Revia should proceed with caution, especially regarding activities requiring full attentiveness. Driving or operating heavy machinery can be risky as the medication may cause drowsiness or impair judgement for some individuals. In high-risk employment, especially in manual labour, it’s essential to discuss your medication with a healthcare provider, as safety is paramount.

Dosage & Adjustments

Standard Regimen represents the core of Revia’s prescribed use. Generally, for adults dealing with opioid use disorder or alcohol use disorder, the typical dosing is 50 mg orally once daily. Regular follow-ups with healthcare providers are vital to assess the ongoing effectiveness of the treatment and adjust dosages if necessary.

Special Cases

Caution is especially needed when prescribing Revia to elderly patients or those with comorbidities. In these cases, liver and kidney functions must be considered. While adjustments may not always be necessary for elderly patients, they should be monitored closely to prevent adverse effects from Revia.

User Testimonials

Feedback from UK patients about Revia is generally positive. Many users on NHS forums describe their recovery paths as significantly enhanced through consistent use of the medication. Testimonials often highlight individual stories illustrating the effectiveness of Revia in managing cravings and supporting long-term recovery goals.

Common Challenges

<pAlongside the success stories, challenges also arise in user experiences. Common concerns revolve around side effects such as nausea or fatigue during the initial adjustment period. Through open discussions on platforms like Patient.info and NHS forums, patients have shared coping strategies to ease into treatment with Revia.

Buying Guide

For those looking to buy Revia, several pharmacy sources in the UK offer it both in-store and online, including major chains such as Boots, LloydsPharmacy, and Superdrug. To obtain Revia legally, a prescription is usually required. However, in some cases, it is possible to buy Revia without a prescription at specific pharmacies.

Price Comparison

When considering the cost of Revia, it's worth comparing NHS prescription charges versus private purchases. On the NHS, standard charges apply, but private purchase may involve different pricing. It’s beneficial to explore both avenues to see which is most cost-effective for your treatment needs.

What’s Inside & How It Works

Understanding what goes into Revia tablets can demystify the medication's role in treating alcohol and opioid dependence. Each component has a purpose that contributes to the overall effectiveness of the drug.

Ingredients Overview

The primary active ingredient in Revia is naltrexone hydrochloride, which acts as an opioid receptor antagonist. This means it blocks the effects of opioids, helping to reduce cravings and prevent relapse. Inactive ingredients, often film-coating and fillers, ensure proper absorption and stability of the tablet. The balance of these components maximises efficacy while minimising side effects.

Mechanism Basics Explained Simply

Naltrexone works by binding to opioid receptors in the brain, preventing the euphoric effects that often trigger cravings. When individuals do not experience the reward typically associated with opioids or alcohol, they are less likely to relapse. This blockade allows those in recovery to focus on their treatment strategies without the overpowering pull of cravings.

Main Indications

Revia is primarily used to aid individuals dealing with alcohol dependence and opioid use disorders. Understanding these approved uses is essential for effective treatment planning.

Approved Uses (MHRA Listing)

According to the MHRA guidelines, Revia is approved for:

• Management of alcohol dependence
• Treatment of opioid use disorder

Off-label Uses in UK Clinics

In some UK clinics, Revia has found use in treating various addiction-related conditions off-label. These can include issues like binge eating disorders and certain forms of substance dependence beyond alcohol and opioids, where blocking cravings may be beneficial.

Interaction Warnings

Interactions with food and drugs are crucial to note for ensuring patient safety while taking Revia.

Food Interactions (Alcohol, Tea/Coffee)

Consuming alcohol while on Revia can lead to severe reactions, including nausea, vomiting, and increased heart rate. It's essential to avoid alcohol altogether to prevent these potentially dangerous side effects. Additionally, caffeine intake from tea and coffee could heighten anxiety levels, a common side effect of naltrexone, making it wise to monitor overall consumption.

Drug Conflicts (MHRA Yellow Card Reports)

Potential drug interactions can occur with opioids, which should be avoided as they can trigger acute withdrawal symptoms. Other medications that may interact include certain antidepressants and antipsychotics. Patients must be aware and should always inform healthcare providers of their current medications.

Latest Evidence & Insights

Recent studies contributed to a growing body of evidence regarding the efficacy and safety of Revia from 2022 to 2025, providing insights into its application in treatment.

Key research highlights include a study that demonstrated the significant reduction in relapse rates for patients with alcohol use disorder when using naltrexone. Additionally, a meta-analysis showed heightened retention rates in treatment programs among those who utilised Revia. These findings confirm the ongoing relevance of Revia in medication-assisted treatment protocols.

Alternative Choices

Exploring alternatives allows clinicians and patients to make informed decisions about treatment options for addiction.

Drug Name	Indication	Mechanism	Pros & Cons
Disulfiram	Alcohol dependence	Alcohol aversive agent	Pros: Effective for some; Cons: Requires compliance
Acamprosate	Alcohol dependence	Modulates glutamate/GABA	Pros: Reduces cravings; Cons: Side effects may vary
Buprenorphine/Suboxone	Opioid dependence	Partial agonist/antagonist	Pros: Allows for less severe withdrawal; Cons: Potential for misuse
Methadone	Opioid dependence	Full agonist	Pros: Long-lasting relief; Cons: Risk of overdose
Nalmefene	Alcohol dependence	Opioid receptor antagonist	Pros: Less frequent dosing; Cons: Not suitable for all

This comparison can guide choices between naltrexone (Revia) and these alternatives, helping individuals find the best fit for their recovery journey.

Regulation Snapshot

The Medicines and Healthcare products Regulatory Agency (MHRA) oversees the approval processes in the UK, ensuring that medications like Revia, which contains naltrexone hydrochloride, meet safety and efficacy standards. Revia is classified as a prescription-only medication (Rx), indicating that it requires a healthcare professional's oversight for safe use. Although it has been discontinued in many regions, generics are widely available, providing alternatives for patients.

For prescribing naltrexone within the NHS, clinicians must navigate a structured regulatory landscape. This includes adhering to national guidelines for the treatment of alcohol and opioid dependence. The regulatory framework emphasises the integration of naltrexone into comprehensive treatment plans that often involve psychosocial support. Additionally, prescribers must monitor patients closely for contraindications, especially those with a history of liver impairment or opioid use.

FAQ Section

Many patients have questions about Revia and its use in treating alcohol and opioid dependence. One common query centres around dosage suitability. The standard recommendation is 50 mg taken orally once daily for adults, but individual needs may vary based on health conditions and treatment goals. It's essential to consult a healthcare provider to determine the right dosage.

Another frequent concern is related to long-term plans when using naltrexone. Typically, treatment duration for alcohol dependence may range from a minimum of three to six months, with continual reassessment advised to tailor the treatment to the patient's ongoing recovery journey. Patients are encouraged to engage actively with healthcare professionals regarding their progress and any side effects.

Guidelines for Proper Use

UK Pharmacist Counselling Style

Pharmacists play a vital role in patient education concerning Revia. They not only dispense the medication but also ensure that patients understand how to use it safely and effectively. A pharmacist's counselling might cover key aspects such as:

• How to take Revia correctly—dosage timing and adherence
• The importance of avoiding opioid use while on naltrexone to prevent withdrawal symptoms
• Potential side effects and what to do if they arise
• Strategies for integrating Revia into a broader treatment plan that includes therapy and support groups

This tailored approach can help demystify the treatment process and foster a supportive environment for those recovering from substance dependence.

NHS Patient Support Advice

Accessing NHS support services can be crucial for individuals using Revia. The NHS offers various resources designed to assist patients in their recovery journey:

• Access to local addiction support services—these often provide additional counselling and support groups.
• Information on lifestyle changes and coping strategies relevant to alcohol or opioid dependence.
• Guidance on how to manage potential side effects experienced during treatment.

Pats are encouraged to utilise these resources to complement their treatment with Revia. Keeping open lines of communication with healthcare professionals can further enhance recovery outcomes.

Delivery Information

City	Region	Delivery Time
London	Greater London	5–7 days
Birmingham	West Midlands	5–7 days
Manchester	Greater Manchester	5–7 days
Glasgow	Scotland	5–7 days
Leeds	West Yorkshire	5–7 days
Liverpool	Merseyside	5–7 days
Bristol	South West	5–7 days
Sheffield	South Yorkshire	5–7 days
Newcastle	North East	5–7 days
Nottingham	East Midlands	5–9 days
Cardiff	Wales	5–9 days
Coventry	West Midlands	5–9 days
Brighton	South East	5–9 days
Reading	South East	5–9 days