Basic Uniphyl Cr Information

• International Nonproprietary Name (INN): Theophylline
• Brand Names Available in United Kingdom: Uniphyl, Theo-24, Elixophyllin, Theochron, Theo-Dur, Pulmophylline, Quibron-T, Theolair
• ATC Code: R03DA04
• Forms & Dosages: Extended-release tablets (100 mg to 600 mg), oral solution (80 mg/15 mL)
• Manufacturers in United Kingdom: Medicis and various generic manufacturers
• Registration Status in United Kingdom: Approved for prescription
• OTC / Rx Classification: Prescription only

Everyday Use & Best Practices

For patients prescribed Uniphyl, establishing a consistent dosing schedule is essential for maintaining steady theophylline levels in the body. By doing so, users can enhance the effectiveness of their treatment while minimising potential side effects.

Many patients find that taking Uniphyl in the morning aligns better with daily routines, effectively reducing night-time side effects such as insomnia. Starting the day with a dose can help set a positive tone, preventing discomfort that could affect the rest of the day.

When considering whether to take Uniphyl with or without food, it is important to note that patients have the flexibility to choose. For some, combining it with meals can mitigate potential gastrointestinal side effects, particularly relevant in the context of a UK diet that is often rich in carbohydrates. This approach not only aids in reducing upset stomach but also adds an element of routine to the medication process.

Overall, consistency is key. Selecting a routine that works best—whether it is before meals, with breakfast, or at another time—is vital. Sticking to this schedule, regardless of food intake, ensures that the benefits of the medication can be fully realised, leading to stable theophylline levels.

What’s Inside & How It Works

Uniphyl is primarily composed of theophylline, a drug classified under bronchodilator agents. This medication is available in extended-release tablets that typically come in dosages of 300 mg and 400 mg, allowing for a slow and sustained release of theophylline into the bloodstream.

Understanding how theophylline works can empower patients to manage their conditions more effectively. It operates by soothing the muscles around the airways, making it easier for individuals with asthma or chronic obstructive pulmonary disease (COPD) to breathe. Beyond merely opening air passages, theophylline is also known for its anti-inflammatory properties, which further enhances airflow. This dual action—bronchodilation and anti-inflammatory effects—makes it particularly beneficial for those grappling with respiratory issues.

Main Indications

Uniphyl is primarily prescribed for chronic asthma and chronic obstructive pulmonary disease (COPD). According to the MHRA guidelines, it serves those who need a bronchodilator yet do not respond adequately to inhaled medication. This is significant for patients seeking effective respiratory treatments.

Interestingly, healthcare providers have also been known to prescribe Uniphyl off-label in UK clinics for conditions like apnea in premature infants. Although this usage is less common, it emphasises the versatility of the medication in broader respiratory care scenarios.

Interaction Warnings

Patients taking Uniphyl should be aware of potential food interactions that may alter the drug's efficacy or absorption. For instance, alcohol can increase the likelihood of side effects, such as nausea or palpitations. Similarly, caffeine-rich products, including tea and coffee, might heighten symptoms like jitteriness, which could be uncomfortable for some users.

On the drug interaction front, the MHRA Yellow Card reporting system has highlighted various conflicts. Certain macrolide antibiotics, anti-seizure medications, and fluoroquinolones can significantly interact with theophylline, resulting in adverse effects. Therefore, it's vital for patients to disclose their complete medication regimen to healthcare providers to avoid any potential complications or toxicity associated with Uniphyl.

Latest Evidence & Insights

Recent studies from the UK and EU, conducted from 2022 to 2025, underline the effectiveness of Uniphyl in treating severe asthma and COPD cases. Patients using theophylline demonstrate marked improvements in lung function and quality of life metrics. Research published in 2023 affirms its role as a valuable secondary therapy for those who do not achieve optimal results with inhaled medications alone.

This emerging evidence signifies a positive trend in respiratory care, reinforcing the need for healthcare providers to remain updated on the latest findings surrounding Uniphyl's efficacy. Patient education on its benefits and mechanisms can also foster better adherence, ultimately leading to improved management of chronic respiratory conditions.

Alternative Choices

Patients often wonder about their options when it comes to managing asthma and COPD, especially if they are considering Uniphyl. While Uniphyl is a widely prescribed treatment, NHS guidelines suggest exploring alternatives that may suit individual needs better.

These alternatives come with their own set of advantages and disadvantages. Inhaled corticosteroids tend to have fewer systemic side effects but necessitate adherence to a strict daily regimen. On the other hand, beta-agonists offer quick relief during acute episodes but may become less effective over time if used excessively. Ultimately, discussing these options with a healthcare professional optimises asthma management choices tailored to individual circumstances.

Regulation Snapshot

Uniphyl is firmly approved by the MHRA, confirming it as an effective option for treating asthma and COPD.

The prescription of Uniphyl within the NHS framework necessitates a thorough evaluation of patients' medical history to ascertain that the benefits surpass any potential risks.

NHS pharmacists play a pivotal role in patient education, offering guidance on the usage of Uniphyl. They often stress the significance of monitoring responses and adjusting dosages to align with individual needs.

FAQ Section

Asthma patients frequently have common queries regarding Uniphyl. Here are a few often-asked questions:

Q: How long does it take for Uniphyl to work?

A: Most patients notice improved breathing within 1–2 hours, while optimal results may take a few days due to its extended-release formulation.

Q: What should I do if I miss a dose?

A: If a dose is missed, it should be taken as soon as remembered, unless it is nearly time for the next dose—then, skip it. Doubling up is not advisable.

Q: Can I stop taking Uniphyl suddenly?

A: It is critical not to discontinue Uniphyl abruptly without consulting a healthcare provider, as this may exacerbate symptoms.

Guidelines for Proper Use

When engaging with patients, pharmacists are likely to highlight the essential aspects of using Uniphyl correctly. The focus should be on:

• Adhering to the prescribed dosage regimen
• Being aware of possible side effects
• Monitoring symptoms and side effects

Furthermore, NHS patient support encourages regular follow-up appointments for monitoring serum levels, especially if there are concerns regarding side effects or interactions with other medications.

Delivery Information